What’ gynecologic pathology 2021: vulva, cervix, uterus, The common hpv-independent lesion differentiated vulvar intraepithelial neoplasia (dvin). presumed rapid progression invasive carcinoma dificulties diagnosis explain dvin represents <10% squamous intraepithelial lesions. – dvin characterized negative patchy p16 mutant-type p53 expression ( full-thickness strong, basal strong, completely negative cytoplasmic staining)..
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